• Molecular NameFludrocortisone
  • SynonymNA
  • Weight380.456
  • Drugbank_IDDB00687
  • ACS_NO127-31-1
  • Show 3D model
  • LogP (experiment)1.49
  • LogP (predicted, AB/LogP v2.0)1.63
  • pkaN/A
  • LogD (pH=7, predicted)1.63
  • Solubility (experiment)0.14 mg/ml
  • LogS (predicted, ACD/Labs)(ph=7)-3.5
  • LogSw (predicted, AB/LogsW2.0)0.11
  • Sw (mg/ml) (predicted, ACD/Labs)0.12
  • No.of HBond Donors3
  • No.of HBond Acceptors5
  • No.of Rotatable Bonds2
  • TPSA94.83
  • StatusFDA approved
  • AdministrationN/A
  • PharmacologyA synthetic corticosteroid with moderate glucocorticoid potency and much greater mineralocorticoid potency.
  • Absorption_valueN/A
  • Absorption (description)N/A
  • Caco_2N/A
  • BioavailabilityN/A
  • Protein bindingN/A
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmHepatic
  • Half life3.5 h
  • ExcretionN/A
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityEffects of overexposure include irritation, cardiac edema, increased blood volume, hypertension, cardiac arrhythmias, enlargement of the heart, headaches, and weakness of the extremities.
  • LD50 (rat)N/A
  • LD50 (mouse)N/A