• Molecular NameCeliprolol
  • SynonymNA
  • Weight379.501
  • Drugbank_IDN/A
  • ACS_NO56980-93-9
  • Show 3D model
  • LogP (experiment)1.92
  • LogP (predicted, AB/LogP v2.0)2.17
  • pka9.68
  • LogD (pH=7, predicted)-0.31
  • Solubility (experiment)N/A
  • LogS (predicted, ACD/Labs)(ph=7)-0.61
  • LogSw (predicted, AB/LogsW2.0)2.45
  • Sw (mg/ml) (predicted, ACD/Labs)0.38
  • No.of HBond Donors3
  • No.of HBond Acceptors7
  • No.of Rotatable Bonds10
  • TPSA90.9
  • StatusN/A
  • AdministrationN/A
  • PharmacologyA medication in the class of beta blockers, used in the treatment of high blood pressure.
  • Absorption_value50.0
  • Absorption (description)Absorbed after oral administration in a non-linear fashion; the percentage of dose absorbed increases with increasing dose.
  • Caco_2N/A
  • Bioavailability40.0
  • Protein binding25.0
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmUndergoes only minimal metabolism
  • Half life5~6 h
  • Excretionexcreted unchanged in the urine (approx. 11%) and faeces (84% in 24 h after an oral dose). After an intravenous dose, approx. 50% is excreted in urine and 31% in faeces. A very low percentage of the drug is excreted as three metabolites.
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityN/A
  • LD50 (rat)N/A
  • LD50 (mouse)N/A