• Molecular NameFluorometholone
  • SynonymFluormetholon; Fluormetholone; Fluoromethalone; FML
  • Weight376.468
  • Drugbank_IDDB00324
  • ACS_NO426-13-1
  • Show 3D model
  • LogP (experiment)2.0
  • LogP (predicted, AB/LogP v2.0)2.56
  • pkaN/A
  • LogD (pH=7, predicted)2.56
  • Solubility (experiment)0.03 mg/ml
  • LogS (predicted, ACD/Labs)(ph=7)-3.89
  • LogSw (predicted, AB/LogsW2.0)0.02
  • Sw (mg/ml) (predicted, ACD/Labs)0.05
  • No.of HBond Donors2
  • No.of HBond Acceptors4
  • No.of Rotatable Bonds1
  • TPSA74.6
  • StatusFDA approved
  • AdministrationN/A
  • PharmacologyA corticosteroid, most often used after laser-based refractive surgery.
  • Absorption_valueN/A
  • Absorption (description)N/A
  • Caco_2N/A
  • BioavailabilityN/A
  • Protein bindingN/A
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmN/A
  • Half lifeN/A
  • ExcretionN/A
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicitySide effects may include acute anterior uveitis and perforation of the globe. Keratitis, conjunctivitis, corneal ulcers, mydriasis, conjunctival hyperemia, loss of accommodation and ptosis have occasionally been reported following local use of corticosteroids.
  • LD50 (rat)LD50 = 234 mg/kg
  • LD50 (mouse)N/A