- Molecular NameCrystal violet
- SynonymGentian Violet
- Weight372.536
- Drugbank_IDDB00406
- ACS_NO14426-25-6, 548-62-9
- Show 2D model
- LogP (experiment)0.51
- LogP (predicted, AB/LogP v2.0)0.69
- pkaN/A
- LogD (pH=7, predicted)0.68
- Solubility (experiment)4 mg/ml
- LogS (predicted, ACD/Labs)(ph=7)N/A
- LogSw (predicted, AB/LogsW2.0)3.33
- Sw (mg/ml) (predicted, ACD/Labs)N/A
- No.of HBond Donors0
- No.of HBond Acceptors3
- No.of Rotatable Bonds4
- TPSA9.49
- StatusFDA approved
- AdministrationN/A
- PharmacologyGentian violet is a mutagen, a mitotic poison, and a clastogen. Gentian violet has been used in medicine for almost 100 years: as an antiseptic for external use, as a topical antibiotic, as a topical antifungal agent, as an antihelminthic agent by oral administration, and more recently, as a blood additive to prevent transmission of Chagas' disease.
- Absorption_valueN/A
- Absorption (description)N/A
- Caco_2N/A
- BioavailabilityN/A
- Protein bindingN/A
- Volume of distribution (VD)N/A
- Blood/Plasma Partitioning ratio (D_blood)N/A
- MetabollsmPrimarily hepatic, mostly demethylation
- Half lifeN/A
- ExcretionN/A
- Urinary ExcretionN/A
- CleranceN/A
- ToxicityOral administration can cause gastrointestinal irritation, and intravenous injection can cause depression in the white blood cell count.
- LD50 (rat)LD50=420 mg/kg
- LD50 (mouse)N/A