• Molecular NameTrimethaphan
  • SynonymThimethaphan; Trimetaphan; Trimetaphanum
  • Weight365.521
  • Drugbank_IDDB01116
  • ACS_NO7187-66-8
  • Show 3D model
  • LogP (experiment)N/A
  • LogP (predicted, AB/LogP v2.0)0.76
  • pkaN/A
  • LogD (pH=7, predicted)0.76
  • Solubility (experiment)N/A
  • LogS (predicted, ACD/Labs)(ph=7)N/A
  • LogSw (predicted, AB/LogsW2.0)0.68
  • Sw (mg/ml) (predicted, ACD/Labs)N/A
  • No.of HBond Donors0
  • No.of HBond Acceptors3
  • No.of Rotatable Bonds4
  • TPSA23.55
  • StatusFDA approved
  • AdministrationOral, IM, IV
  • PharmacologyA drug that counteracts cholinergic transmission at the ganglion type of nicotinic receptors of the autonomic ganglia and therefore blocks both the sympathetic nervous system and the parasympathetic nervous system.
  • Absorption_valueN/A
  • Absorption (description)N/A
  • Caco_2N/A
  • BioavailabilityN/A
  • Protein bindingN/A
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmN/A
  • Half lifeN/A
  • ExcretionRenal, mostly unchanged
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityN/A
  • LD50 (rat)N/A
  • LD50 (mouse)N/A