- Molecular NameZolpidem
- SynonymZolpidem tartrate; Zolpidemum [Latin]
- Weight363.505
- Drugbank_IDDB00425
- ACS_NO82626-48-0
- Show 2D model
- LogP (experiment)3.85
- LogP (predicted, AB/LogP v2.0)4.45
- pka6.2
- LogD (pH=7, predicted)4.41
- Solubility (experiment)N/A
- LogS (predicted, ACD/Labs)(ph=7)-4.3
- LogSw (predicted, AB/LogsW2.0)0.0
- Sw (mg/ml) (predicted, ACD/Labs)0.01
- No.of HBond Donors0
- No.of HBond Acceptors4
- No.of Rotatable Bonds7
- TPSA38.13
- StatusFDA approved
- AdministrationN/A
- PharmacologyA prescription medication used for the short-term treatment of insomnia, as well as some brain disorders.
- Absorption_value95.0
- Absorption (description)N/A
- Caco_2N/A
- Bioavailability72.0
- Protein binding92.0
- Volume of distribution (VD)0.68 L/kg
- Blood/Plasma Partitioning ratio (D_blood)N/A
- MetabollsmMetabolically cleared predominantly by CYP3A4.
- Half life1.9 h
- Excretion56% renal, 34% fecal
- Urinary Excretion<1
- Clerance4.5 ml/min/kg
- ToxicityN/A
- LD50 (rat)N/A
- LD50 (mouse)N/A