• Molecular NameButylscopolamine
  • Synonymscopolamine butylbromide; butylhyoscine; hyoscine butylbromide
  • Weight360.474
  • Drugbank_IDN/A
  • ACS_NO146-64-4
  • Show 3D model
  • LogP (experiment)N/A
  • LogP (predicted, AB/LogP v2.0)-1.08
  • pkaN/A
  • LogD (pH=7, predicted)-1.08
  • Solubility (experiment)N/A
  • LogS (predicted, ACD/Labs)(ph=7)-0.3
  • LogSw (predicted, AB/LogsW2.0)296.66
  • Sw (mg/ml) (predicted, ACD/Labs)179.05
  • No.of HBond Donors1
  • No.of HBond Acceptors5
  • No.of Rotatable Bonds8
  • TPSA68.29
  • StatusN/A
  • AdministrationOral, rectal, intravenous
  • PharmacologyA peripherally acting antimuscarinic, anticholinergic agent used as an abdominal-specific antispasmodic.
  • Absorption_value10.0
  • Absorption (description)N/A
  • Caco_2N/A
  • Bioavailability1.0
  • Protein bindingN/A
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmThe main metabolic pathway is hydrolytic cleavage of the ester bond. The main metabolites are tropic acid and scopine butylbromide.
  • Half life5 h
  • ExcretionN/A
  • Urinary ExcretionRenal (50%) and fecal
  • CleranceN/A
  • ToxicityN/A
  • LD50 (rat)N/A
  • LD50 (mouse)N/A