• Molecular NameTolrestat
  • SynonymNA
  • Weight357.352
  • Drugbank_IDN/A
  • ACS_NO82964-04-3
  • Show 3D model
  • LogP (experiment)N/A
  • LogP (predicted, AB/LogP v2.0)3.99
  • pkaN/A
  • LogD (pH=7, predicted)0.15
  • Solubility (experiment)0.149 mg/ml
  • LogS (predicted, ACD/Labs)(ph=7)-1.21
  • LogSw (predicted, AB/LogsW2.0)0.01
  • Sw (mg/ml) (predicted, ACD/Labs)0.05
  • No.of HBond Donors1
  • No.of HBond Acceptors4
  • No.of Rotatable Bonds6
  • TPSA81.86
  • StatusN/A
  • AdministrationN/A
  • PharmacologyAn aldose reductase inhibitor which was approved for the control of certain diabetic complications.
  • Absorption_value66.0
  • Absorption (description)N/A
  • Caco_2N/A
  • BioavailabilityN/A
  • Protein bindingN/A
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmN/A
  • Half lifeN/A
  • ExcretionN/A
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityN/A
  • LD50 (rat)N/A
  • LD50 (mouse)N/A