• Molecular NameConjugated Estrogens
  • SynonymEstrogens; Estrone Estrone Hydrogen Sulfate; Estrone Hydrogen Sulfate; Estrone Sodium Sulfate; Estrone Sulfate; Estrone Sulfate Sodium; Estrone Sulphate; Estrone-sulfate; Oestrone Sulphate; Sodium Estrone Sulfate
  • Weight349.427
  • Drugbank_IDDB00286
  • ACS_NO12126-59-9
  • Show 2D model
  • LogP (experiment)N/A
  • LogP (predicted, AB/LogP v2.0)0.06
  • pkaN/A
  • LogD (pH=7, predicted)-4.04
  • Solubility (experiment)0.0036 mg/ml
  • LogS (predicted, ACD/Labs)(ph=7)-1.69
  • LogSw (predicted, AB/LogsW2.0)0.1
  • Sw (mg/ml) (predicted, ACD/Labs)7.19
  • No.of HBond Donors1
  • No.of HBond Acceptors5
  • No.of Rotatable Bonds2
  • TPSA89.05
  • StatusFDA approved
  • AdministrationOral, topical
  • PharmacologyA form of hormone replacement therapy.
  • Absorption_valueN/A
  • Absorption (description)Well absorbed
  • Caco_2N/A
  • BioavailabilityN/A
  • Protein binding90.0
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmN/A
  • Half life7.2 h
  • Excretionrenal
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityNausea and vomiting
  • LD50 (rat)N/A
  • LD50 (mouse)N/A