NavDB ID:  NA0026

PubChem CID:  3878

ChEMBL ID:  CHEMBL741

IUPAC Name:  6-(2,3-dichlorophenyl)-1,2,4-triazine-3,5-diamine

SMILES:  Nc1nnc(-c2cccc(Cl)c2Cl)c(N)n1

MF:  C₉H₇Cl₂N₅   MW:  256.09g/mol

IC₅₀/EC₅₀* (nM):  10000nM

Target:  Nav1.2

Binding Site:  8

Organism:  Human

Article DOI:  10.1016/j.bmc.2008.05.003   PMID:  18501613

NavDB ID:  NA0027

PubChem CID:  3878

ChEMBL ID:  CHEMBL741

IUPAC Name:  6-(2,3-dichlorophenyl)-1,2,4-triazine-3,5-diamine

SMILES:  Nc1nnc(-c2cccc(Cl)c2Cl)c(N)n1

MF:  C₉H₇Cl₂N₅   MW:  256.09g/mol

IC₅₀/EC₅₀* (nM):  >100000nM

Target:  Nav1.2

Binding Site:  8

Organism:  Rat

Article DOI:  10.1016/j.bmc.2009.03.067   PMID:  19394229

NavDB ID:  NA0028

PubChem CID:  3878

ChEMBL ID:  CHEMBL741

IUPAC Name:  6-(2,3-dichlorophenyl)-1,2,4-triazine-3,5-diamine

SMILES:  Nc1nnc(-c2cccc(Cl)c2Cl)c(N)n1

MF:  C₉H₇Cl₂N₅   MW:  256.09g/mol

IC₅₀/EC₅₀* (nM):  17000nM

Target:  Nav1.2

Binding Site:  8

Organism:  Human

Article DOI:  10.1021/acsmedchemlett.5b00059   PMID:  26101568

NavDB ID:  NA0029

PubChem CID:  3878

ChEMBL ID:  CHEMBL741

IUPAC Name:  6-(2,3-dichlorophenyl)-1,2,4-triazine-3,5-diamine

SMILES:  Nc1nnc(-c2cccc(Cl)c2Cl)c(N)n1

MF:  C₉H₇Cl₂N₅   MW:  256.09g/mol

IC₅₀/EC₅₀* (nM):  35000nM

Target:  Nav1.2

Binding Site:  8

Organism:  Human

Article DOI:  10.1021/jm801432r   PMID:  19388676

NavDB ID:  NA0030

PubChem CID:  3878

ChEMBL ID:  CHEMBL741

IUPAC Name:  6-(2,3-dichlorophenyl)-1,2,4-triazine-3,5-diamine

SMILES:  Nc1nnc(-c2cccc(Cl)c2Cl)c(N)n1

MF:  C₉H₇Cl₂N₅   MW:  256.09g/mol

IC₅₀/EC₅₀* (nM):  17000nM

Target:  Nav1.3

Binding Site:  8

Organism:  Human

Article DOI:  10.1021/acsmedchemlett.5b00059   PMID:  26101568