NavDB ID:  NA0031

PubChem CID:  3878

ChEMBL ID:  CHEMBL741

IUPAC Name:  6-(2,3-dichlorophenyl)-1,2,4-triazine-3,5-diamine

SMILES:  Nc1nnc(-c2cccc(Cl)c2Cl)c(N)n1

MF:  C₉H₇Cl₂N₅   MW:  256.09g/mol

IC₅₀/EC₅₀* (nM):  62000nM

Target:  Nav1.5

Binding Site:  8

Organism:  Human

Article DOI:  10.1016/j.bmc.2008.05.003   PMID:  18501613

NavDB ID:  NA0032

PubChem CID:  3878

ChEMBL ID:  CHEMBL741

IUPAC Name:  6-(2,3-dichlorophenyl)-1,2,4-triazine-3,5-diamine

SMILES:  Nc1nnc(-c2cccc(Cl)c2Cl)c(N)n1

MF:  C₉H₇Cl₂N₅   MW:  256.09g/mol

IC₅₀/EC₅₀* (nM):  39811nM

Target:  Nav1.5

Binding Site:  8

Organism:  Human

Article DOI:  10.1016/j.vascn.2014.07.002   PMID:  25087753

NavDB ID:  NA0033

PubChem CID:  3878

ChEMBL ID:  CHEMBL741

IUPAC Name:  6-(2,3-dichlorophenyl)-1,2,4-triazine-3,5-diamine

SMILES:  Nc1nnc(-c2cccc(Cl)c2Cl)c(N)n1

MF:  C₉H₇Cl₂N₅   MW:  256.09g/mol

IC₅₀/EC₅₀* (nM):  100000nM

Target:  Nav1.5

Binding Site:  8

Organism:  Human

Article DOI:  10.1016/j.vascn.2014.07.002   PMID:  25087753

NavDB ID:  NA0034

PubChem CID:  3878

ChEMBL ID:  CHEMBL741

IUPAC Name:  6-(2,3-dichlorophenyl)-1,2,4-triazine-3,5-diamine

SMILES:  Nc1nnc(-c2cccc(Cl)c2Cl)c(N)n1

MF:  C₉H₇Cl₂N₅   MW:  256.09g/mol

IC₅₀/EC₅₀* (nM):  17000nM

Target:  Nav1.7

Binding Site:  8

Organism:  Human

Article DOI:  10.1021/acsmedchemlett.5b00059   PMID:  26101568

NavDB ID:  NA0035

PubChem CID:  3878

ChEMBL ID:  CHEMBL741

IUPAC Name:  6-(2,3-dichlorophenyl)-1,2,4-triazine-3,5-diamine

SMILES:  Nc1nnc(-c2cccc(Cl)c2Cl)c(N)n1

MF:  C₉H₇Cl₂N₅   MW:  256.09g/mol

IC₅₀/EC₅₀* (nM):  25000nM

Target:  Nav1.8

Binding Site:  8

Organism:  Rat

Article DOI:  10.1016/j.bmc.2008.05.003   PMID:  18501613