NavDB Target ID	NAT009
Name	Sodium channel protein type 11 subunit alpha
Synonyms	Peripheral nerve sodium channel 5 Sensory neuron sodium channel 2 Sodium channel protein type XI subunit alpha Voltage-gated sodium channel subunit alpha Nav1.9 hNaN
Description	This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which sodium ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-resistant sodium channel isoform. Also involved, with the contribution of the receptor tyrosine kinase NTRK2, in rapid BDNF-evoked neuronal depolarization.
Organism	Human, Mouse, Rat
UniProt	Q9UI33, Q9R053, O88457

NavDB ID	Sructure	ChEMBL ID	Molecular Formula	IC50/EC50* (nM)	Binding Site	Organism	Article DOI