• Molecular NameFlucytosine
  • Synonym5-FC; 5-Fluorocystosine; 5-Fluorocytosin; 5-Fluorocytosine; 5-Flurocytosine; Flucytosin; Fluocytosine; Fluorcytosine
  • Weight129.094
  • Drugbank_IDDB01099
  • ACS_NO2022-85-7
  • Show 3D model
  • LogP (experiment)N/A
  • LogP (predicted, AB/LogP v2.0)-1.21
  • pka2.9, 10.7
  • LogD (pH=7, predicted)-1.21
  • Solubility (experiment)10.5 mg/ml
  • LogS (predicted, ACD/Labs)(ph=7)-0.4
  • LogSw (predicted, AB/LogsW2.0)6.99
  • Sw (mg/ml) (predicted, ACD/Labs)50.97
  • No.of HBond Donors3
  • No.of HBond Acceptors4
  • No.of Rotatable Bonds0
  • TPSA67.48
  • StatusFDA approved
  • AdministrationOral, intravenous
  • PharmacologyA synthetic antimycotic drug.
  • Absorption_value100.0
  • Absorption (description)Rapidly and virtually completely absorbed following oral administration. Bioavailability 78% to 89%.
  • Caco_2N/A
  • Bioavailability84.0
  • Protein binding29.5
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmMinimal, in the GI tract
  • Half life2.4~4.8 h
  • ExcretionRenal (90%)
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityN/A
  • LD50 (rat)LD50 = >15 gm/kg.
  • LD50 (mouse)N/A