- Molecular NameAmyl Nitrite
- Synonym3-Methylbutanol nitrite; 3-Methylbutyl nitrite; Amilnitrit; Amilnitrite; Amyl nitrit; Amyl nitrite I; Amyl nitrosum; IPN; Isoamyl nitrite; Isopentyl nitrite; Nitramyl; Nitrous acid, 3-methylbutyl ester; Nitrous acid, isopentyl ester; Pentanoli nitris; Pentyl nitrite
- Weight117.148
- Drugbank_IDDB01612
- ACS_NO8017-89-8
- Show 3D model
- LogP (experiment)2.8
- LogP (predicted, AB/LogP v2.0)1.32
- pkaN/A
- LogD (pH=7, predicted)1.32
- Solubility (experiment)Insoluble
- LogS (predicted, ACD/Labs)(ph=7)-1.32
- LogSw (predicted, AB/LogsW2.0)23.78
- Sw (mg/ml) (predicted, ACD/Labs)5.55
- No.of HBond Donors0
- No.of HBond Acceptors3
- No.of Rotatable Bonds4
- TPSA38.66
- StatusFDA approved
- AdministrationN/A
- PharmacologyIn common with other alkyl nitrites, is a potent vasodilator, i.e., it expands blood vessels, resulting in lowering of the blood pressure.
- Absorption_valueN/A
- Absorption (description)Absorbed from the mucous membranes after inhalation but rapidly inactivated by hydrolysis. Inactive after ingestion owing to hydrolysis in the gastro-intestinal tract.
- Caco_2N/A
- BioavailabilityN/A
- Protein bindingN/A
- Volume of distribution (VD)N/A
- Blood/Plasma Partitioning ratio (D_blood)N/A
- MetabollsmN/A
- Half lifeN/A
- ExcretionN/A
- Urinary ExcretionN/A
- CleranceN/A
- ToxicityRecovery has occurred after the ingestion of 12 mL.
- LD50 (rat)N/A
- LD50 (mouse)N/A