- Molecular NameMetaraminol
- SynonymHydroxynorephedrine; L-Metaraminol; M-Hydroxy Norephedrine; M-Hydroxyphenylpropanolamine; M-Hydroxypropadrine; Metaraminol Bitartrate; Metaraminolum [INN-Latin]; Metaraminolum [Latin]
- Weight167.208
- Drugbank_IDDB00610
- ACS_NO54-49-9
- Show 3D model
- LogP (experiment)-0.27
- LogP (predicted, AB/LogP v2.0)-0.27
- pkaN/A
- LogD (pH=7, predicted)-2.2
- Solubility (experiment)N/A
- LogS (predicted, ACD/Labs)(ph=7)0.78
- LogSw (predicted, AB/LogsW2.0)58.87
- Sw (mg/ml) (predicted, ACD/Labs)87.24
- No.of HBond Donors4
- No.of HBond Acceptors3
- No.of Rotatable Bonds2
- TPSA66.48
- StatusFDA approved
- AdministrationIntravenous
- PharmacologyA potent sympathomimetic amine used in the prevention and treatment of hypotension, particularly as a complication of anesthesia. It is an α1-adrenergic receptor agonist with some β effect.
- Absorption_valueN/A
- Absorption (description)N/A
- Caco_2N/A
- BioavailabilityN/A
- Protein binding45.0
- Volume of distribution (VD)N/A
- Blood/Plasma Partitioning ratio (D_blood)N/A
- MetabollsmHepatic
- Half lifeN/A
- ExcretionN/A
- Urinary ExcretionN/A
- CleranceN/A
- ToxicityN/A
- LD50 (rat)N/A
- LD50 (mouse)N/A