• Molecular NameMetaraminol
  • SynonymHydroxynorephedrine; L-Metaraminol; M-Hydroxy Norephedrine; M-Hydroxyphenylpropanolamine; M-Hydroxypropadrine; Metaraminol Bitartrate; Metaraminolum [INN-Latin]; Metaraminolum [Latin]
  • Weight167.208
  • Drugbank_IDDB00610
  • ACS_NO54-49-9
  • Show 3D model
  • LogP (experiment)-0.27
  • LogP (predicted, AB/LogP v2.0)-0.27
  • pkaN/A
  • LogD (pH=7, predicted)-2.2
  • Solubility (experiment)N/A
  • LogS (predicted, ACD/Labs)(ph=7)0.78
  • LogSw (predicted, AB/LogsW2.0)58.87
  • Sw (mg/ml) (predicted, ACD/Labs)87.24
  • No.of HBond Donors4
  • No.of HBond Acceptors3
  • No.of Rotatable Bonds2
  • TPSA66.48
  • StatusFDA approved
  • AdministrationIntravenous
  • PharmacologyA potent sympathomimetic amine used in the prevention and treatment of hypotension, particularly as a complication of anesthesia. It is an α1-adrenergic receptor agonist with some β effect.
  • Absorption_valueN/A
  • Absorption (description)N/A
  • Caco_2N/A
  • BioavailabilityN/A
  • Protein binding45.0
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmHepatic
  • Half lifeN/A
  • ExcretionN/A
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityN/A
  • LD50 (rat)N/A
  • LD50 (mouse)N/A