• Molecular NamePhenylbutyrate
  • SynonymNA
  • Weight164.204
  • Drugbank_IDN/A
  • ACS_NO1716-12-7
  • Show 3D model
  • LogP (experiment)N/A
  • LogP (predicted, AB/LogP v2.0)2.22
  • pkaN/A
  • LogD (pH=7, predicted)0.03
  • Solubility (experiment)N/A
  • LogS (predicted, ACD/Labs)(ph=7)0.2
  • LogSw (predicted, AB/LogsW2.0)0.49
  • Sw (mg/ml) (predicted, ACD/Labs)1.59
  • No.of HBond Donors1
  • No.of HBond Acceptors2
  • No.of Rotatable Bonds4
  • TPSA37.3
  • StatusN/A
  • AdministrationN/A
  • PharmacologyIt has been used to treat urea cycle disorders.
  • Absorption_valueN/A
  • Absorption (description)N/A
  • Caco_2N/A
  • Bioavailability78.0
  • Protein bindingN/A
  • Volume of distribution (VD)5 L/kg
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmPhenylbutyrate is a prodrug. In the human body it is metabolized by beta-oxidation to phenylacetate.
  • Half lifeN/A
  • Excretion80% as phenylacetylglutamine
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityN/A
  • LD50 (rat)N/A
  • LD50 (mouse)N/A