- Molecular NamePhenylbutyrate
- SynonymNA
- Weight164.204
- Drugbank_IDN/A
- ACS_NO1716-12-7
- Show 3D model
- LogP (experiment)N/A
- LogP (predicted, AB/LogP v2.0)2.22
- pkaN/A
- LogD (pH=7, predicted)0.03
- Solubility (experiment)N/A
- LogS (predicted, ACD/Labs)(ph=7)0.2
- LogSw (predicted, AB/LogsW2.0)0.49
- Sw (mg/ml) (predicted, ACD/Labs)1.59
- No.of HBond Donors1
- No.of HBond Acceptors2
- No.of Rotatable Bonds4
- TPSA37.3
- StatusN/A
- AdministrationN/A
- PharmacologyIt has been used to treat urea cycle disorders.
- Absorption_valueN/A
- Absorption (description)N/A
- Caco_2N/A
- Bioavailability78.0
- Protein bindingN/A
- Volume of distribution (VD)5 L/kg
- Blood/Plasma Partitioning ratio (D_blood)N/A
- MetabollsmPhenylbutyrate is a prodrug. In the human body it is metabolized by beta-oxidation to phenylacetate.
- Half lifeN/A
- Excretion80% as phenylacetylglutamine
- Urinary ExcretionN/A
- CleranceN/A
- ToxicityN/A
- LD50 (rat)N/A
- LD50 (mouse)N/A