- Molecular NameMethamphetamine
- Synonym(+ )-methylamphetamine; (+)-(s)-deoxyephedrine; (+)-(s)-n-alpha-dimethylphenethylamine; (+)-2-(N-Methylamino)-1-phenylpropane; (+)-methamphetamine; (+)-methylamphetamine; (+)-n-methylamphetamine; (+)-n,alpha-dimethyl-beta-phenylethylamine; (+)-n,alpha-dimethylphenethylamine; (2S)-N-methyl-1-phenylpropan-2-amine; (s)-(+)-deoxyephedrine; (s)-(+)-methamphetamine; (s)-(+)-n,alpha,dimethylphenethylamine; (s)-methamphetamine; (s)-methylamphetamine; (s)-n,alpha-dimethylbenzeneethanamine; (s)-n,alpha-dimethylbenzeneethanoamine; 1-Phenyl-2-methylamino-propan [German]; 1-Phenyl-2-methylaminopropane; 2S-(+)-Methamphetamine; D-(s)-methamphetamine; d-1-Phenyl-2-methylaminopropan [German]; D-1-Phenyl-2-methylaminopropane; D-deoxyephedrine; D-desoxyephedrine; D-methamphetamine; D-methylamphetamine; D-n-methylamphetamine; D-n,alpha-dimethylphenethylamine; D-phenylisopropylmethylamine; Desoxyephedrine hydrochloride; Ice; L-methamphetamine; Metamfetamina [inn-spanish]; Metamfetaminum [inn-latin]; Metamphetamine; Metanfetamina [inn-spanish]; Meth; Methamphetaminum [inn-latin]; Methyl-beta-phenylisopropylamine; Methylamphetamine; N-Methyl-1-phenyl-2-propanamine; N-methyl-beta-phenylisopropylamin [german]; N-methyl-beta-phenylisopropylamine; N-methylamphetamine; S-(+)-methamphetamine
- Weight149.237
- Drugbank_IDDB01577
- ACS_NO537-46-2
- Show 3D model
- LogP (experiment)2.07
- LogP (predicted, AB/LogP v2.0)2.25
- pkaN/A
- LogD (pH=7, predicted)-0.64
- Solubility (experiment)N/A
- LogS (predicted, ACD/Labs)(ph=7)0.83
- LogSw (predicted, AB/LogsW2.0)5.0
- Sw (mg/ml) (predicted, ACD/Labs)6.58
- No.of HBond Donors1
- No.of HBond Acceptors1
- No.of Rotatable Bonds3
- TPSA12.03
- StatusFDA approved
- AdministrationOral Recreational: Oral, I.V., I.M., Insufflation, Inhalation, Rectal
- PharmacologyA psychostimulant and sympathomimetic drug.
- Absorption_valueN/A
- Absorption (description)N/A
- Caco_2N/A
- Bioavailability67.0
- Protein bindingN/A
- Volume of distribution (VD)N/A
- Blood/Plasma Partitioning ratio (D_blood)N/A
- MetabollsmMain metabolites of methamphetamine are amphetamine[1], 4-hydroxymethamphetamine, 4-hydroxyamphetamine and some of the methamphetamine remains unchanged until excretion.
- Half life9~15 h
- ExcretionIt is excreted by the kidneys, and its half-life depends on urinary pH.
- Urinary ExcretionN/A
- CleranceN/A
- ToxicityN/A
- LD50 (rat)N/A
- LD50 (mouse)N/A