• Molecular NameCarbachol
  • SynonymNA
  • Weight147.198
  • Drugbank_IDDB00411
  • ACS_NO51-83-2
  • Show 3D model
  • LogP (experiment)-3.8
  • LogP (predicted, AB/LogP v2.0)-4.19
  • pka4.8
  • LogD (pH=7, predicted)-4.19
  • Solubility (experiment)1000 mg/ml
  • LogS (predicted, ACD/Labs)(ph=7)0.42
  • LogSw (predicted, AB/LogsW2.0)5029.98
  • Sw (mg/ml) (predicted, ACD/Labs)387.51
  • No.of HBond Donors2
  • No.of HBond Acceptors4
  • No.of Rotatable Bonds4
  • TPSA52.32
  • StatusFDA approved
  • AdministrationTablet, liquid, eye drops
  • PharmacologyA drug that binds and activates the acetylcholine receptor. Thus it is classified as a cholinergic agonist. It is primarily used for various ophthalmic purposes, such as for treating glaucoma, or for use during ophthalmic surgery. It is generally administered as an ophthalmic solution (i.e. eyedrops).
  • Absorption_valueN/A
  • Absorption (description)N/A
  • Caco_2N/A
  • BioavailabilityN/A
  • Protein bindingN/A
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmN/A
  • Half lifeN/A
  • ExcretionN/A
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityOral, mouse: LD50 = 15 mg/kg; Oral, rat: LD50 = 40 mg/kg.
  • LD50 (rat)N/A
  • LD50 (mouse)N/A