• Molecular NameAcetanilide
  • SynonymN-phenylacetamide; acetanil; acetanilid
  • Weight135.166
  • Drugbank_IDN/A
  • ACS_NO103-84-4
  • Show 3D model
  • LogP (experiment)1.16
  • LogP (predicted, AB/LogP v2.0)1.47
  • pkaN/A
  • LogD (pH=7, predicted)1.47
  • Solubility (experiment)5.38 mg/ml
  • LogS (predicted, ACD/Labs)(ph=7)-1.38
  • LogSw (predicted, AB/LogsW2.0)3.24
  • Sw (mg/ml) (predicted, ACD/Labs)5.6
  • No.of HBond Donors1
  • No.of HBond Acceptors2
  • No.of Rotatable Bonds1
  • TPSA29.1
  • StatusN/A
  • AdministrationN/A
  • PharmacologyAcetanilide was the first aniline derivative serendipitously found to possess analgesic as well as antipyretic properties, and was quickly introduced into medical practice under the name of Antifebrin by A. Cahn and P. Hepp in 1886. But its (apparent) unacceptable toxic effects.
  • Absorption_valueN/A
  • Absorption (description)Percent intestinal absorption of the compound was determined in rat: 43%
  • Caco_2N/A
  • BioavailabilityN/A
  • Protein bindingN/A
  • Volume of distribution (VD)N/A
  • Blood/Plasma Partitioning ratio (D_blood)N/A
  • MetabollsmN/A
  • Half lifeN/A
  • ExcretionN/A
  • Urinary ExcretionN/A
  • CleranceN/A
  • ToxicityN/A
  • LD50 (rat)N/A
  • LD50 (mouse)N/A