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Inhibitors

Name:  (E)-N-[4-[(3R)-3-[[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]-1-piperidyl]phenyl]-4-(dimethylamino)but-2-enamide

Formula:  C29H32ClN7O

Similarity:  0.8596491228070176

Relative Targets:   Cyclin-dependent kinase 12  |

Name:  (E)-N-[6-[(3R)-3-[[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]-1-piperidyl]-3-pyridyl]but-2-enamide

Formula:  C26H26ClN7O

Similarity:  0.8214285714285714

Relative Targets:   Cyclin-dependent kinase 12  |

Name:  (E)-N-[4-[(3R)-3-[[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]-1-piperidyl]-2-methyl-phenyl]but-2-enamide

Formula:  C28H29ClN6O

Similarity:  0.8070175438596491

Relative Targets:   Cyclin-dependent kinase 12  |

Name:  (E)-N-[4-[(3R)-3-[[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]-1-piperidyl]-3-fluoro-phenyl]but-2-enamide

Formula:  C27H26ClFN6O

Similarity:  0.8070175438596491

Relative Targets:   Cyclin-dependent kinase 12  |

Name:  (E)-N-[4-[(1R,3R)-3-[[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]cyclohexoxy]phenyl]but-2-enamide

Formula:  C28H28ClN5O2

Similarity:  0.7542372881355932

Relative Targets:   Cyclin-dependent kinase 12  |

Name:  (E)-N-[6-[(3R)-3-[[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]-1-piperidyl]-3-pyridyl]-4-(dimethylamino)but-2-enamide

Formula:  C28H31ClN8O

Similarity:  0.7096774193548387

Relative Targets:   Cyclin-dependent kinase 12  |

Name:  (E)-N-[4-[(3R)-3-[[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]piperidine-1-carbonyl]phenyl]-4-(dimethylamino)but-2-enamide

Formula:  C30H32ClN7O2

Similarity:  0.7086614173228346

Relative Targets:   Cyclin-dependent kinase 12  |

Name:  (E)-N-[4-[(3R)-3-[[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]-1-piperidyl]-5-fluoro-2-methyl-phenyl]but-2-enamide

Formula:  C28H28ClFN6O

Similarity:  0.7049180327868853

Relative Targets:   Cyclin-dependent kinase 12  |

Name:  (E)-N-[4-[(3R)-3-[[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]-1-piperidyl]-5-methoxy-2-methyl-phenyl]but-2-enamide

Formula:  C29H31ClN6O2

Similarity:  0.688

Relative Targets:   Cyclin-dependent kinase 12  |

Name:  (E)-N-[4-[(3R)-3-[[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]azepane-1-carbonyl]phenyl]-4-(dimethylamino)but-2-enamide

Formula:  C31H34ClN7O2

Similarity:  0.6793893129770993

Relative Targets:   Cyclin-dependent kinase 12  |

Name:  (E)-N-[4-[(3R)-3-[[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]pyrrolidine-1-carbonyl]phenyl]-4-(dimethylamino)but-2-enamide

Formula:  C29H30ClN7O2

Similarity:  0.671875

Relative Targets:   Cyclin-dependent kinase 12  |

Name:  (E)-N-[4-[(1R,3R)-3-[[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]cyclohexoxy]phenyl]-4-(dimethylamino)but-2-enamide

Formula:  C30H33ClN6O2

Similarity:  0.6538461538461539

Relative Targets:   Cyclin-dependent kinase 12  |

Name:  (E)-N-[4-[(1S,3R)-3-[[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]cyclohexoxy]phenyl]-4-(dimethylamino)but-2-enamide

Formula:  C30H33ClN6O2

Similarity:  0.6538461538461539

Relative Targets:   Cyclin-dependent kinase 12  |

Name:  N-[6-[(3R)-3-[[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]piperidine-1-carbonyl]-3-pyridyl]prop-2-enamide

Formula:  C26H24ClN7O2

Similarity:  0.648

Relative Targets:   Cyclin-dependent kinase 12  |

Name:  (E)-N-[6-[(3R)-3-[[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]piperidine-1-carbonyl]-3-pyridyl]-4-(dimethylamino)but-2-enamide

Formula:  C29H31ClN8O2

Similarity:  0.6439393939393939

Relative Targets:   Cyclin-dependent kinase 12  |

Name:  (E)-N-[4-[(3R)-3-[[5-bromo-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]piperidine-1-carbonyl]phenyl]-4-(dimethylamino)but-2-enamide

Formula:  C30H32BrN7O2

Similarity:  0.631578947368421

Relative Targets:   Cyclin-dependent kinase 12  |

Name:  N-[3-[[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]cyclohexyl]-4-[[(Z)-4-(dimethylamino)but-2-enoyl]amino]benzamide

Formula:  C31H34ClN7O2

Similarity:  0.6296296296296297

Relative Targets:   Cyclin-dependent kinase 7  |

Name:  N-[4-[[5-Chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]phenyl]prop-2-enamide

Formula:  C21H16ClN5O

Similarity:  0.6052631578947368

Relative Targets:   Epidermal growth factor receptor  |

Name:  (E)-N-[4-[(3R)-3-[[5-cyclopropyl-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]piperidine-1-carbonyl]phenyl]-4-(dimethylamino)but-2-enamide

Formula:  C33H37N7O2

Similarity:  0.60431654676259

Relative Targets:   Cyclin-dependent kinase 12  |