Searching results

Name:  Rociletinib

Formula:  C₂₇H₂₈F₃N₇O₃

Similarity:  0.8360655737704918

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-[4-(4-acetylpiperazin-1-yl)-2-methoxy-anilino]-5-(trifluoromethyl)pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C₂₇H₂₇F₃N₆O₄

Similarity:  0.6842105263157895

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide

Formula:  C₂₅H₂₈ClN₇O₂

Similarity:  0.5939849624060151

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[7-[3-methoxy-4-(4-methylpiperazin-1-yl)anilino]-3-methyl-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide

Formula:  C₂₈H₃₂N₈O₃

Similarity:  0.5704225352112676

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[2-methoxy-4-(4-morpholino-1-piperidyl)anilino]-5-(trifluoromethyl)pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide

Formula:  C₃₁H₃₅F₃N₈O₄

Similarity:  0.567741935483871

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-[4-(4-methylpiperazin-1-yl)anilino]-5-(trifluoromethyl)pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C₂₅H₂₅F₃N₆O₂

Similarity:  0.5620437956204379

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[5-isopropyl-2-[3-methoxy-4-(4-methylpiperazin-1-yl)anilino]-6,7-dioxo-pteridin-8-yl]phenyl]prop-2-enamide

Formula:  C₃₀H₃₄N₈O₄

Similarity:  0.5436241610738255

Relative Targets:   Epidermal growth factor receptor  |

Name:  2-[3-[[2-[4-(4-acetylpiperazin-1-yl)-2-methoxy-anilino]-5-chloro-pyrimidin-4-yl]amino]anilino]ethanesulfonyl fluoride

Formula:  C25H29ClFN7O4S

Similarity:  0.5416666666666666

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[4-(4-acetylpiperazin-1-yl)-2-methoxy-anilino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide

Formula:  C30H31N7O4

Similarity:  0.5369127516778524

Relative Targets:   Tyrosine-protein kinase JAK3  |

Name:  N-methyl-2-[[2-[4-[4-[(2S)-2-(prop-2-enoylamino)propanoyl]piperazin-1-yl]anilino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]benzamide

Formula:  C29H31F3N8O3

Similarity:  0.5364238410596026

Relative Targets:   Focal adhesion kinase 1  |

Name:  N-methyl-2-[[2-[4-[4-[(2R)-2-(prop-2-enoylamino)propanoyl]piperazin-1-yl]anilino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]benzamide

Formula:  C29H31F3N8O3

Similarity:  0.5364238410596026

Relative Targets:   Focal adhesion kinase 1  |

Name:  N-methyl-2-[[2-[4-[4-[2-(prop-2-enoylamino)propanoyl]piperazin-1-yl]anilino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]benzamide

Formula:  C29H31F3N8O3

Similarity:  0.5364238410596026

Relative Targets:   Focal adhesion kinase 1  |

Name:  N-methyl-2-[[2-[4-[4-[2-(prop-2-enoylamino)acetyl]piperazin-1-yl]anilino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]benzamide

Formula:  C28H29F3N8O3

Similarity:  0.5333333333333333

Relative Targets:   Focal adhesion kinase 1  |

Name:  N-[3-[5-chloro-2-[4-(4-methylpiperazin-1-yl)-2-(trifluoromethyl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

Formula:  C₂₅H₂₄ClF₃N₆O₂

Similarity:  0.5319148936170213

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[2-[3-methoxy-4-(4-methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide

Formula:  C27H29N7O3

Similarity:  0.5314685314685315

Relative Targets:   Epidermal growth factor receptor  |

Name:  [2-[[2-[3-(4-Acetylpiperazin-1-yl)anilino]-5-chloropyrimidin-4-yl]amino]phenyl] prop-2-enoate

Formula:  C₂₅H₂₅ClN₆O₃

Similarity:  0.5251798561151079

Relative Targets:   Mitogen-activated protein kinase kinase kinase 7  | Dual specificity mitogen-activated protein kinase kinase 1  |

Name:  Jak3-IN-1

Formula:  C₂₆H₃₀ClN₇O₂

Similarity:  0.5140845070422535

Relative Targets:   Serine/threonine-protein kinase Sgk1  | Epidermal growth factor receptor  | Platelet-derived growth factor receptor beta  | Tyrosine-protein kinase JAK1  | Non-receptor tyrosine-protein kinase TYK2  | Dual specificity protein kinase TTK  | Receptor-type tyrosine-protein kinase FLT3  | Tyrosine-protein kinase Blk  | Tyrosine-protein kinase JAK3  | Focal adhesion kinase 1  | Tyrosine-protein kinase BTK  | Tyrosine-protein kinase ITK/TSK  | Receptor tyrosine-protein kinase erbB-4  |

Name:  N-[3-[[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide

Formula:  C₂₆H₃₀N₈O₃

Similarity:  0.5138888888888888

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[[6-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-3-(trifluoromethyl)-2-pyridyl]oxy]phenyl]prop-2-enamide

Formula:  C₂₇H₂₈F₃N₅O₃

Similarity:  0.5103448275862069

Relative Targets:   Dipeptidyl peptidase 1  |