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Approved Drugs
Name: Sotorasib
Formula: C30H30F2N6O3
Similarity: 0.8524590163934426
Inhibitors
Name: 6-chloro-7-(2-fluoro-6-hydroxy-phenyl)-1-(4-isopropyl-6-methyl-pyrimidin-5-yl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C29H29ClFN7O3
Similarity: 0.8991596638655462
Relative Targets: GTPase KRas |
Name: 6-fluoro-7-(2-fluoro-6-hydroxy-phenyl)-1-(2-isopropyl-4-methyl-3-pyridyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C30H30F2N6O3
Similarity: 0.8524590163934426
Relative Targets: GTPase KRas |
Name: 6-fluoro-7-(2-fluoro-6-hydroxy-phenyl)-1-(4-isopropyl-2-methyl-3-pyridyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C30H30F2N6O3
Similarity: 0.8373983739837398
Relative Targets: GTPase KRas |
Name: 6-chloro-1-(4,6-diisopropylpyrimidin-5-yl)-7-(2-fluoro-6-hydroxy-phenyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C31H33ClFN7O3
Similarity: 0.7906976744186046
Relative Targets: GTPase KRas |
Name: 6-fluoro-7-(2-fluoro-6-hydroxy-phenyl)-1-(2-isopropyl-6-methyl-phenyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C31H31F2N5O3
Similarity: 0.7795275590551181
Relative Targets: GTPase KRas |
Name: 6-chloro-7-(2-fluoro-6-hydroxy-phenyl)-1-(2-isopropyl-4-methyl-3-pyridyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C30H30ClFN6O3
Similarity: 0.765625
Relative Targets: GTPase KRas |
Name: 6-chloro-7-(2-fluoro-6-hydroxy-phenyl)-1-(4-isopropyl-2-methyl-3-pyridyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C30H30ClFN6O3
Similarity: 0.751937984496124
Relative Targets: GTPase KRas |
Name: 1-(4,6-diisopropylpyrimidin-5-yl)-8-fluoro-7-(2-fluoro-6-hydroxy-phenyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[4,3-d]pyrimidin-2-one
Formula: C31H33F2N7O3
Similarity: 0.7238805970149254
Relative Targets: GTPase KRas |
Name: 8-fluoro-7-(2-fluoro-6-hydroxy-phenyl)-1-(2-isopropyl-4-methyl-3-pyridyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[4,3-d]pyrimidin-2-one
Formula: C30H30F2N6O3
Similarity: 0.7121212121212122
Relative Targets: GTPase KRas |
Name: 6-chloro-7-(2-fluoro-6-hydroxy-phenyl)-1-(2-isopropyl-6-methyl-phenyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C31H31ClFN5O3
Similarity: 0.6992481203007519
Relative Targets: GTPase KRas |
Name: 8-chloro-1-(4,6-diisopropylpyrimidin-5-yl)-7-(2-fluoro-6-hydroxy-phenyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[4,3-d]pyrimidin-2-one
Formula: C31H33ClFN7O3
Similarity: 0.6985294117647058
Relative Targets: GTPase KRas |
Name: 8-chloro-7-(2-fluoro-6-hydroxy-phenyl)-1-(2-isopropyl-4-methyl-3-pyridyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[4,3-d]pyrimidin-2-one
Formula: C30H30ClFN6O3
Similarity: 0.6865671641791045
Relative Targets: GTPase KRas |
Name: 6-chloro-7-(2-fluoro-6-hydroxy-phenyl)-1-(2-isopropyl-4-methyl-pyrazol-3-yl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C28H29ClFN7O3
Similarity: 0.6766917293233082
Relative Targets: GTPase KRas |
Name: 6-chloro-7-(2-fluoro-6-hydroxy-phenyl)-1-(3-isopropyl-2-pyridyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C29H28ClFN6O3
Similarity: 0.6716417910447762
Relative Targets: GTPase KRas |
Name: 6-chloro-1-(4,6-dipropylpyrimidin-5-yl)-7-(2-fluoro-6-hydroxy-phenyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C31H33ClFN7O3
Similarity: 0.6642857142857143
Relative Targets: GTPase KRas |
Name: 6-chloro-7-(2-fluoro-6-hydroxy-phenyl)-1-(2-isopropylpyrazol-3-yl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C27H27ClFN7O3
Similarity: 0.6492537313432836
Relative Targets: GTPase KRas |
Name: 6-chloro-7-(2-fluoro-6-hydroxy-phenyl)-1-(4-isopropyl-4H-thiazol-5-yl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C27H28ClFN6O3S
Similarity: 0.6492537313432836
Relative Targets: GTPase KRas |
Name: 6-chloro-7-(2-fluoro-6-hydroxy-phenyl)-1-(2-isopropylphenyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C30H29ClFN5O3
Similarity: 0.6470588235294118
Relative Targets: GTPase KRas |
Name: 6-chloro-1-(2-ethyl-6-methyl-phenyl)-7-(2-fluoro-6-hydroxy-phenyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C30H29ClFN5O3
Similarity: 0.6470588235294118
Relative Targets: GTPase KRas |