Searching results
Approved Drugs
Name: Sotorasib
Formula: C30H30F2N6O3
Similarity: 0.7238805970149254
Inhibitors
Name: 6-chloro-7-(2-fluoro-6-hydroxy-phenyl)-1-(4-isopropyl-6-methyl-pyrimidin-5-yl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C29H29ClFN7O3
Similarity: 0.8780487804878049
Relative Targets: GTPase KRas |
Name: 8-chloro-1-(4,6-diisopropylpyrimidin-5-yl)-7-(2-fluoro-6-hydroxy-phenyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[4,3-d]pyrimidin-2-one
Formula: C31H33ClFN7O3
Similarity: 0.8294573643410853
Relative Targets: GTPase KRas |
Name: 6-chloro-7-(2-fluoro-6-hydroxy-phenyl)-1-(2-isopropyl-4-methyl-3-pyridyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C30H30ClFN6O3
Similarity: 0.8046875
Relative Targets: GTPase KRas |
Name: 1-(4,6-diisopropylpyrimidin-5-yl)-8-fluoro-7-(2-fluoro-6-hydroxy-phenyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[4,3-d]pyrimidin-2-one
Formula: C31H33F2N7O3
Similarity: 0.8015267175572519
Relative Targets: GTPase KRas |
Name: 6-fluoro-7-(2-fluoro-6-hydroxy-phenyl)-1-(4-isopropyl-6-methyl-pyrimidin-5-yl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C29H29F2N7O3
Similarity: 0.7906976744186046
Relative Targets: Tyrosine-protein kinase BTK |
Name: 6-chloro-7-(2-fluoro-6-hydroxy-phenyl)-1-(4-isopropyl-2-methyl-3-pyridyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C30H30ClFN6O3
Similarity: 0.7633587786259542
Relative Targets: GTPase KRas |
Name: 6-chloro-7-(2-fluoro-6-hydroxy-phenyl)-1-(2-isopropyl-6-methyl-phenyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C31H31ClFN5O3
Similarity: 0.7368421052631579
Relative Targets: GTPase KRas |
Name: 6-fluoro-7-(2-fluoro-6-hydroxy-phenyl)-1-(2-isopropyl-4-methyl-3-pyridyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C30H30F2N6O3
Similarity: 0.7238805970149254
Relative Targets: GTPase KRas |
Name: 6-chloro-7-(2-fluoro-6-hydroxy-phenyl)-1-(3-isopropyl-2-pyridyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C29H28ClFN6O3
Similarity: 0.7218045112781954
Relative Targets: GTPase KRas |
Name: 6-chloro-7-(2-fluoro-6-hydroxy-phenyl)-1-(2-isopropyl-4-methyl-pyrazol-3-yl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C28H29ClFN7O3
Similarity: 0.7142857142857143
Relative Targets: GTPase KRas |
Name: 6-chloro-1-(4,6-dipropylpyrimidin-5-yl)-7-(2-fluoro-6-hydroxy-phenyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C31H33ClFN7O3
Similarity: 0.7122302158273381
Relative Targets: GTPase KRas |
Name: 6-chloro-7-(2-fluoro-6-hydroxy-phenyl)-1-(2-isopropylpyrazol-3-yl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C27H27ClFN7O3
Similarity: 0.6992481203007519
Relative Targets: GTPase KRas |
Name: 6-chloro-7-(2-fluoro-6-hydroxy-phenyl)-1-(4-isopropyl-4H-thiazol-5-yl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C27H28ClFN6O3S
Similarity: 0.6992481203007519
Relative Targets: GTPase KRas |
Name: 6-chloro-7-(2-fluoro-6-hydroxy-phenyl)-1-(2-isopropylphenyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C30H29ClFN5O3
Similarity: 0.6962962962962963
Relative Targets: GTPase KRas |
Name: 6-fluoro-7-(2-fluoro-6-hydroxy-phenyl)-1-(4-isopropyl-2-methyl-3-pyridyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C30H30F2N6O3
Similarity: 0.6861313868613139
Relative Targets: GTPase KRas |
Name: 6-chloro-1-(2-ethyl-6-methyl-phenyl)-7-(2-fluoro-6-hydroxy-phenyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C30H29ClFN5O3
Similarity: 0.6838235294117647
Relative Targets: GTPase KRas |
Name: 8-chloro-7-(2-fluoro-6-hydroxy-phenyl)-1-(2-isopropyl-4-methyl-3-pyridyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[4,3-d]pyrimidin-2-one
Formula: C30H30ClFN6O3
Similarity: 0.6739130434782609
Relative Targets: GTPase KRas |
Name: 6-fluoro-7-(2-fluoro-6-hydroxy-phenyl)-1-(2-isopropyl-6-methyl-phenyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C31H31F2N5O3
Similarity: 0.6618705035971223
Relative Targets: GTPase KRas |
Name: 1-(2-tert-butylphenyl)-6-chloro-7-(2-fluoro-6-hydroxy-phenyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C31H31ClFN5O3
Similarity: 0.65
Relative Targets: GTPase KRas |