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Approved Drugs
Name: Sotorasib
Formula: C30H30F2N6O3
Similarity: 0.7099236641221374
Inhibitors
Name: 6-chloro-7-(2-fluoro-6-hydroxy-phenyl)-1-(2-isopropylphenyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C30H29ClFN5O3
Similarity: 0.8347107438016529
Relative Targets: GTPase KRas |
Name: 6-chloro-7-(2-fluoro-6-hydroxy-phenyl)-1-(2-isopropyl-6-methyl-phenyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C31H31ClFN5O3
Similarity: 0.8211382113821138
Relative Targets: GTPase KRas |
Name: 6-chloro-7-(2-fluoro-6-hydroxy-phenyl)-1-(4-isopropyl-2-methyl-3-pyridyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C30H30ClFN6O3
Similarity: 0.8211382113821138
Relative Targets: GTPase KRas |
Name: 6-chloro-7-(2-fluoro-6-hydroxy-phenyl)-1-(2-isopropyl-4-methyl-3-pyridyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C30H30ClFN6O3
Similarity: 0.792
Relative Targets: GTPase KRas |
Name: 6-chloro-7-(2-fluoro-6-hydroxy-phenyl)-1-(2-isopropylpyrazol-3-yl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C27H27ClFN7O3
Similarity: 0.7804878048780488
Relative Targets: GTPase KRas |
Name: 6-chloro-7-(2-fluoro-6-hydroxy-phenyl)-1-(4-isopropyl-6-methyl-pyrimidin-5-yl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C29H29ClFN7O3
Similarity: 0.75
Relative Targets: GTPase KRas |
Name: 6-chloro-7-(2-fluoro-6-hydroxy-phenyl)-1-(2-isopropyl-4-methyl-pyrazol-3-yl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C28H29ClFN7O3
Similarity: 0.7401574803149606
Relative Targets: GTPase KRas |
Name: 6-chloro-7-(2-fluoro-6-hydroxy-phenyl)-1-(4-isopropyl-4H-thiazol-5-yl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C27H28ClFN6O3S
Similarity: 0.7380952380952381
Relative Targets: GTPase KRas |
Name: 6-fluoro-7-(2-fluoro-6-hydroxy-phenyl)-1-(2-isopropyl-6-methyl-phenyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C31H31F2N5O3
Similarity: 0.7364341085271318
Relative Targets: GTPase KRas |
Name: 6-fluoro-7-(2-fluoro-6-hydroxy-phenyl)-1-(4-isopropyl-2-methyl-3-pyridyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C30H30F2N6O3
Similarity: 0.7364341085271318
Relative Targets: GTPase KRas |
Name: 6-chloro-1-(2-ethyl-6-methyl-phenyl)-7-(2-fluoro-6-hydroxy-phenyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C30H29ClFN5O3
Similarity: 0.734375
Relative Targets: GTPase KRas |
Name: 1-(2-tert-butylphenyl)-6-chloro-7-(2-fluoro-6-hydroxy-phenyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C31H31ClFN5O3
Similarity: 0.7230769230769231
Relative Targets: GTPase KRas |
Name: 6-chloro-1-(4,6-diisopropylpyrimidin-5-yl)-7-(2-fluoro-6-hydroxy-phenyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C31H33ClFN7O3
Similarity: 0.7218045112781954
Relative Targets: GTPase KRas |
Name: 6-chloro-7-(2-fluoro-6-hydroxy-phenyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]-1-(2-propylphenyl)pyrido[2,3-d]pyrimidin-2-one
Formula: C30H29ClFN5O3
Similarity: 0.7153846153846154
Relative Targets: GTPase KRas |
Name: 6-fluoro-7-(2-fluoro-6-hydroxy-phenyl)-1-(2-isopropyl-4-methyl-3-pyridyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C30H30F2N6O3
Similarity: 0.7099236641221374
Relative Targets: GTPase KRas |
Name: 6-chloro-7-(2-fluoro-6-hydroxy-phenyl)-1-(2-isopropylphenyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]quinazolin-2-one
Formula: C31H30ClFN4O3
Similarity: 0.6946564885496184
Relative Targets: GTPase KRas |
Name: 6-chloro-7-(2-fluorophenyl)-1-(2-isopropylphenyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C30H29ClFN5O2
Similarity: 0.6923076923076923
Relative Targets: GTPase KRas |
Name: 6-chloro-7-(2-hydroxyphenyl)-1-(2-isopropylphenyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C30H30ClN5O3
Similarity: 0.6923076923076923
Relative Targets: GTPase KRas |
Name: 6-chloro-7-(2-fluoro-6-hydroxy-phenyl)-1-(2-isopropylphenyl)-4-(4-prop-2-enoylpiperazin-1-yl)pyrido[2,3-d]pyrimidin-2-one
Formula: C29H27ClFN5O3
Similarity: 0.6793893129770993
Relative Targets: GTPase KRas |