Searching results
Approved Drugs
Name: Sotorasib
Formula: C30H30F2N6O3
Similarity: 0.751937984496124
Inhibitors
Name: 6-fluoro-7-(2-fluoro-6-hydroxy-phenyl)-1-(2-isopropyl-6-methyl-phenyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C31H31F2N5O3
Similarity: 0.8991596638655462
Relative Targets: GTPase KRas |
Name: 6-chloro-7-(2-fluoro-6-hydroxy-phenyl)-1-(4-isopropyl-2-methyl-3-pyridyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C30H30ClFN6O3
Similarity: 0.8524590163934426
Relative Targets: GTPase KRas |
Name: 6-chloro-1-(2-ethyl-6-methyl-phenyl)-7-(2-fluoro-6-hydroxy-phenyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C30H29ClFN5O3
Similarity: 0.8512396694214877
Relative Targets: GTPase KRas |
Name: 6-chloro-7-(2-fluoro-6-hydroxy-phenyl)-1-(2-isopropyl-4-methyl-3-pyridyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C30H30ClFN6O3
Similarity: 0.8373983739837398
Relative Targets: GTPase KRas |
Name: 6-chloro-7-(2-fluoro-6-hydroxy-phenyl)-1-(2-isopropylphenyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C30H29ClFN5O3
Similarity: 0.8360655737704918
Relative Targets: GTPase KRas |
Name: 6-chloro-7-(2-fluoro-6-hydroxy-phenyl)-1-(3-isopropyl-2-pyridyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C29H28ClFN6O3
Similarity: 0.8211382113821138
Relative Targets: GTPase KRas |
Name: 6-chloro-7-(2-fluoro-6-hydroxy-phenyl)-1-(4-isopropyl-6-methyl-pyrimidin-5-yl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C29H29ClFN7O3
Similarity: 0.7795275590551181
Relative Targets: GTPase KRas |
Name: 6-fluoro-7-(2-fluoro-6-hydroxy-phenyl)-1-(4-isopropyl-2-methyl-3-pyridyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C30H30F2N6O3
Similarity: 0.765625
Relative Targets: GTPase KRas |
Name: 6-chloro-7-(2-fluoro-6-hydroxy-phenyl)-1-(2-isopropyl-4-methyl-pyrazol-3-yl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C28H29ClFN7O3
Similarity: 0.7559055118110236
Relative Targets: GTPase KRas |
Name: 6-fluoro-7-(2-fluoro-6-hydroxy-phenyl)-1-(2-isopropyl-4-methyl-3-pyridyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C30H30F2N6O3
Similarity: 0.751937984496124
Relative Targets: GTPase KRas |
Name: 6-chloro-7-(2-fluoro-6-hydroxy-phenyl)-1-(2-isopropylpyrazol-3-yl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C27H27ClFN7O3
Similarity: 0.7401574803149606
Relative Targets: GTPase KRas |
Name: 1-(2-tert-butylphenyl)-6-chloro-7-(2-fluoro-6-hydroxy-phenyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C31H31ClFN5O3
Similarity: 0.7384615384615385
Relative Targets: GTPase KRas |
Name: 6-chloro-1-(4,6-diisopropylpyrimidin-5-yl)-7-(2-fluoro-6-hydroxy-phenyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C31H33ClFN7O3
Similarity: 0.7368421052631579
Relative Targets: GTPase KRas |
Name: 6-chloro-7-(2-fluoro-6-hydroxy-phenyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]-1-(2-propylphenyl)pyrido[2,3-d]pyrimidin-2-one
Formula: C30H29ClFN5O3
Similarity: 0.7175572519083969
Relative Targets: GTPase KRas |
Name: 6-chloro-7-(2-fluoro-6-hydroxy-phenyl)-1-(4-isopropyl-4H-thiazol-5-yl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C27H28ClFN6O3S
Similarity: 0.7131782945736435
Relative Targets: GTPase KRas |
Name: 6-fluoro-7-(2-fluoro-6-hydroxy-phenyl)-1-(4-isopropyl-6-methyl-pyrimidin-5-yl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C29H29F2N7O3
Similarity: 0.6992481203007519
Relative Targets: Tyrosine-protein kinase BTK |
Name: 1-(2,6-diisopropylphenyl)-8-fluoro-7-(2-fluoro-6-hydroxy-phenyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[4,3-d]pyrimidin-2-one
Formula: C33H35F2N5O3
Similarity: 0.6985294117647058
Relative Targets: GTPase KRas |
Name: 6-chloro-7-(2-fluoro-6-hydroxy-phenyl)-1-(2-isopropylphenyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]quinazolin-2-one
Formula: C31H30ClFN4O3
Similarity: 0.696969696969697
Relative Targets: GTPase KRas |
Name: 6-chloro-7-(2-fluorophenyl)-1-(2-isopropylphenyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C30H29ClFN5O2
Similarity: 0.6946564885496184
Relative Targets: GTPase KRas |