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Approved Drugs
Name: Sotorasib
Formula: C30H30F2N6O3
Similarity: 0.5416666666666666
Inhibitors
Name: 6-chloro-7-(2-fluoro-6-hydroxy-phenyl)-1-(2-isopropylphenyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C30H29ClFN5O3
Similarity: 0.8181818181818182
Relative Targets: GTPase KRas |
Name: 6-chloro-7-(2-fluoro-6-hydroxy-phenyl)-1-(2-isopropylphenyl)-4-(4-prop-2-enoylpiperazin-1-yl)quinazolin-2-one
Formula: C30H28ClFN4O3
Similarity: 0.8166666666666667
Relative Targets: GTPase KRas |
Name: 6-chloro-7-(2-fluorophenyl)-1-(2-isopropylphenyl)-4-(4-prop-2-enoylpiperazin-1-yl)quinazolin-2-one
Formula: C30H28ClFN4O2
Similarity: 0.7007874015748031
Relative Targets: GTPase KRas |
Name: 6-chloro-7-(2-fluoro-6-hydroxy-phenyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]-1-(2-propylphenyl)pyrido[2,3-d]pyrimidin-2-one
Formula: C30H29ClFN5O3
Similarity: 0.6870229007633588
Relative Targets: GTPase KRas |
Name: 1-(2-tert-butylphenyl)-6-chloro-7-(2-fluoro-6-hydroxy-phenyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C31H31ClFN5O3
Similarity: 0.6818181818181818
Relative Targets: GTPase KRas |
Name: 6-chloro-7-(2-fluoro-6-hydroxy-phenyl)-1-(2-isopropyl-6-methyl-phenyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C31H31ClFN5O3
Similarity: 0.6818181818181818
Relative Targets: GTPase KRas |
Name: 6-chloro-7-(2-fluoro-6-hydroxy-phenyl)-1-(3-isopropyl-2-pyridyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C29H28ClFN6O3
Similarity: 0.6793893129770993
Relative Targets: GTPase KRas |
Name: 6-chloro-7-(2-fluorophenyl)-1-(2-isopropylphenyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C30H29ClFN5O2
Similarity: 0.676923076923077
Relative Targets: GTPase KRas |
Name: 6-chloro-7-(2-hydroxyphenyl)-1-(2-isopropylphenyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C30H30ClN5O3
Similarity: 0.676923076923077
Relative Targets: GTPase KRas |
Name: 1-[4-[7-chloro-6-(2-fluoro-6-hydroxy-phenyl)-4-(2-isopropylphenyl)phthalazin-1-yl]piperazin-1-yl]prop-2-en-1-one
Formula: C30H28ClFN4O2
Similarity: 0.6744186046511628
Relative Targets: GTPase KRas |
Name: 6-chloro-7-(2-fluoro-6-hydroxy-phenyl)-1-(2-isopropylphenyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]quinazolin-2-one
Formula: C31H30ClFN4O3
Similarity: 0.6666666666666666
Relative Targets: GTPase KRas |
Name: 1-[4-[6-chloro-7-(2-fluoro-6-hydroxy-phenyl)-1-(2-isopropylphenyl)quinazolin-1-ium-4-yl]piperazin-1-yl]prop-2-en-1-one
Formula: C30H29ClFN4O2+
Similarity: 0.6363636363636364
Relative Targets: GTPase KRas |
Name: 6-chloro-7-(2-fluoro-6-hydroxy-phenyl)-1-(4-isopropyl-2-methyl-3-pyridyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C30H30ClFN6O3
Similarity: 0.6323529411764706
Relative Targets: GTPase KRas |
Name: 6-chloro-1-(2-isopropylphenyl)-7-(5-methyl-1H-indazol-4-yl)-4-(4-prop-2-enoylpiperazin-1-yl)quinazolin-2-one
Formula: C32H31ClN6O2
Similarity: 0.6304347826086957
Relative Targets: GTPase KRas |
Name: 6-chloro-7-(2-chlorophenyl)-1-(2-isopropylphenyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C30H29Cl2N5O2
Similarity: 0.6268656716417911
Relative Targets: GTPase KRas |
Name: 6-chloro-7-(2-fluoro-6-hydroxy-phenyl)-1-(2-isopropyl-4-methyl-3-pyridyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C30H30ClFN6O3
Similarity: 0.6086956521739131
Relative Targets: GTPase KRas |
Name: 6-fluoro-7-(2-fluoro-6-hydroxy-phenyl)-1-(2-isopropyl-6-methyl-phenyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C31H31F2N5O3
Similarity: 0.6086956521739131
Relative Targets: GTPase KRas |
Name: 6-chloro-7-(2-fluoro-6-hydroxy-phenyl)-1-(2-isopropylpyrazol-3-yl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C27H27ClFN7O3
Similarity: 0.6074074074074074
Relative Targets: GTPase KRas |
Name: 6-chloro-1-(2-ethyl-6-methyl-phenyl)-7-(2-fluoro-6-hydroxy-phenyl)-4-[(2S)-2-methyl-4-prop-2-enoyl-piperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Formula: C30H29ClFN5O3
Similarity: 0.6058394160583942
Relative Targets: GTPase KRas |