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Approved Drugs
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Inhibitors
Name:  N-[3-[5-methyl-2-[[6-(4-methylpiperazin-1-yl)-3-pyridyl]amino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide
Formula:  C27H28N8O2
Similarity:  0.6991869918699187
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[[2-[[1-(1-methyl-4-piperidyl)pyrazol-4-yl]amino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide
Formula:  C26H28N8O2
Similarity:  0.6967213114754098
Relative Targets:   Tyrosine-protein kinase JAK3  |
Name:  N-[3-[2-[[1-[2-(dimethylamino)ethyl]pyrazol-4-yl]amino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide
Formula:  C24H26N8O2
Similarity:  0.6722689075630253
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[5-methyl-2-[(5-methyl-6,7-dihydro-4H-thiazolo[5,4-c]pyridin-2-yl)amino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide
Formula:  C24H23N7O2S
Similarity:  0.6260162601626016
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[2-[2-Methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxopyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide
Formula:  C29H31N7O3
Similarity:  0.6212121212121212
Relative Targets:   Epidermal growth factor receptor  | Tyrosine-protein kinase JAK3  |
Name:  N-[3-[2-[4-(3,4-dimethylpiperazin-1-yl)-2-methoxy-anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide
Formula:  C30H33N7O3
Similarity:  0.5882352941176471
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[2-[4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide
Formula:  C26H26N8O2
Similarity:  0.5681818181818182
Relative Targets:   Epidermal growth factor receptor  | Tyrosine-protein kinase BTK  |
Name:  N-[3-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-7-oxo-pteridin-8-yl]phenyl]prop-2-enamide
Formula:  C27H28N8O3
Similarity:  0.5474452554744526
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[2-[2-methoxy-4-(3,4,5-trimethylpiperazin-1-yl)anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide
Formula:  C31H35N7O3
Similarity:  0.5460992907801419
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[2-[3-Amino-6-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]pyrazin-2-yl]imidazo[4,5-c]pyridin-1-yl]phenyl]prop-2-enamide
Formula:  C28H28N10O
Similarity:  0.5428571428571428
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[2-[3-Amino-6-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]pyrazin-2-yl]imidazo[4,5-c]pyridin-3-yl]phenyl]prop-2-enamide
Formula:  C28H28N10O
Similarity:  0.5428571428571428
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[2-[3-Amino-6-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]pyrazin-2-yl]benzimidazol-1-yl]phenyl]prop-2-enamide
Formula:  C29H29N9O
Similarity:  0.5428571428571428
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]-5-methyl-phenyl]prop-2-enamide
Formula:  C30H33N7O3
Similarity:  0.5428571428571428
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-fluoro-5-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide
Formula:  C29H30FN7O3
Similarity:  0.5428571428571428
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-bromo-5-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide
Formula:  C29H30BrN7O3
Similarity:  0.5428571428571428
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-chloro-5-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide
Formula:  C29H30ClN7O3
Similarity:  0.5428571428571428
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-ethyl-5-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide
Formula:  C31H35N7O3
Similarity:  0.5314685314685315
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[7-oxo-2-(4-pyrrolidin-1-ylanilino)pteridin-8-yl]phenyl]prop-2-enamide
Formula:  C25H23N7O2
Similarity:  0.5303030303030303
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide
Formula:  C30H33N7O3
Similarity:  0.528169014084507
Relative Targets:   Tyrosine-protein kinase JAK3  |