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Approved Drugs
Inhibitors
Name:  (E)-4-(dimethylamino)-N-[4-(3-ethynylanilino)-7-tetrahydropyran-4-yloxy-quinazolin-6-yl]but-2-enamide
Formula:  C27H29N5O3
Similarity:  0.8952380952380953
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-ethynylanilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(isopropylamino)but-2-enamide
Formula:  C27H29N5O3
Similarity:  0.8256880733944955
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[4-(3-ethynylanilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]prop-2-enamide
Formula:  C23H20N4O3
Similarity:  0.7961165048543689
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-4-(dimethylamino)-N-[4-(3-ethynylanilino)-7-[(1-methyl-4-piperidyl)oxy]quinazolin-6-yl]but-2-enamide
Formula:  C28H32N6O2
Similarity:  0.7946428571428571
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-4-(cyclopropylamino)-N-[4-(3-ethynylanilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]but-2-enamide
Formula:  C27H27N5O3
Similarity:  0.7857142857142857
Relative Targets:   Epidermal growth factor receptor  |
Name:  Afatinib
Formula:  C24H25ClFN5O3
Similarity:  0.7727272727272727
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-2  | Dipeptidyl peptidase 1  |
Name:  (E)-N-[4-(3-cyano-4-fluoro-anilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula:  C25H25FN6O3
Similarity:  0.7678571428571429
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-chloro-4-fluoro-anilino)-6-[(3R)-tetrahydrofuran-3-yl]oxy-quinazolin-7-yl]-4-(dimethylamino)but-2-enamide
Formula:  C24H25ClFN5O3
Similarity:  0.7410714285714286
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-(3-ethynylanilino)-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(1-piperidyl)but-2-enamide
Formula:  C29H31N5O3
Similarity:  0.7394957983193278
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-4-[cyclopropyl(methyl)amino]-N-[4-(3-ethynylanilino)-7-methoxy-quinazolin-6-yl]but-2-enamide
Formula:  C25H25N5O2
Similarity:  0.7339449541284404
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-[4-chloro-3-(trifluoromethyl)anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula:  C25H25ClF3N5O3
Similarity:  0.7264957264957265
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-4-(dimethylamino)-N-[4-(3-ethynylanilino)-7-(2-methoxyethoxy)quinazolin-6-yl]but-2-enamide
Formula:  C25H27N5O3
Similarity:  0.7142857142857143
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-4-[cyclopropyl(methyl)amino]-N-[7-ethoxy-4-(3-ethynylanilino)quinazolin-6-yl]but-2-enamide
Formula:  C26H27N5O2
Similarity:  0.7142857142857143
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula:  C31H31ClFN5O4
Similarity:  0.6717557251908397
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-4-(cyclopropylamino)-N-[4-(3-ethynylanilino)-7-methoxy-quinazolin-6-yl]but-2-enamide
Formula:  C24H23N5O2
Similarity:  0.6696428571428571
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-4-(dimethylamino)-N-[4-[4-[(3-fluorophenyl)methoxy]anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]but-2-enamide
Formula:  C31H32FN5O4
Similarity:  0.6692307692307692
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-[3-chloro-4-(2-pyridylmethoxy)anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Formula:  C30H31ClN6O4
Similarity:  0.6692307692307692
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-4-(dimethylamino)-N-[4-[4-(2-pyridylmethoxy)anilino]-7-[(3S)-tetrahydrofuran-3-yl]oxy-quinazolin-6-yl]but-2-enamide
Formula:  C30H32N6O4
Similarity:  0.6538461538461539
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-4-(cyclopropylamino)-N-[7-ethoxy-4-(3-ethynylanilino)quinazolin-6-yl]but-2-enamide
Formula:  C25H25N5O2
Similarity:  0.6521739130434783
Relative Targets:   Epidermal growth factor receptor  |