Searching results

Approved Drugs

Name:  Mobocertinib

Formula:  C32H39N7O4

Similarity:  0.8145161290322581

Name:  Osimertinib

Formula:  C28H33N7O2

Similarity:  0.8103448275862069

Inhibitors

Name:  N-[5-[[5-chloro-4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]-2-[2-(dimethylamino)ethyl-methyl-amino]-4-methoxy-phenyl]prop-2-enamide

Formula:  C28H32ClN7O2

Similarity:  0.8928571428571429

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[5-[[5-cyano-4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]-2-[2-(dimethylamino)ethyl-methyl-amino]-4-methoxy-phenyl]prop-2-enamide

Formula:  C29H32N8O2

Similarity:  0.8695652173913043

Relative Targets:   Epidermal growth factor receptor  |

Name:  Osimertinib

Formula:  C28H33N7O2

Similarity:  0.8103448275862069

Relative Targets:   Epidermal growth factor receptor  | Dipeptidyl peptidase 1  |

Name:  N-[2-[2-(Dimethylamino)ethyl-methylamino]-4-methoxy-5-[[6-(1-methylindol-3-yl)pyrazin-2-yl]amino]phenyl]prop-2-enamide

Formula:  C28H33N7O2

Similarity:  0.7647058823529411

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[2-[2-(dimethylamino)ethyl-methyl-amino]-4-methoxy-5-[[2-(1-methylindol-3-yl)pyrimidin-4-yl]amino]phenyl]prop-2-enamide

Formula:  C28H33N7O2

Similarity:  0.7647058823529411

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[5-[[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]-2-[2-(dimethylamino)ethyl-methyl-amino]-4-methoxy-phenyl]prop-2-enamide

Formula:  C27H30ClN7O2

Similarity:  0.7213114754098361

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[5-[(5-chloro-4-pyrazolo[1,5-a]pyridin-3-yl-pyrimidin-2-yl)amino]-2-[2-(dimethylamino)ethyl-methyl-amino]-4-methoxy-phenyl]prop-2-enamide

Formula:  C26H29ClN8O2

Similarity:  0.6935483870967742

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[4-methoxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]-2-[methyl-[2-(methylamino)ethyl]amino]phenyl]prop-2-enamide

Formula:  C27H31N7O2

Similarity:  0.6910569105691057

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[2-[2-(dimethylamino)ethyl-methyl-amino]-4-methoxy-5-[[6-(1-methylindol-3-yl)-1H-indazol-3-yl]amino]phenyl]prop-2-enamide

Formula:  C31H35N7O2

Similarity:  0.6846153846153846

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[2-[2-(dimethylamino)ethyl-methyl-amino]-5-[[4-(1H-indol-3-yl)pyrimidin-2-yl]amino]-4-methoxy-phenyl]prop-2-enamide

Formula:  C27H31N7O2

Similarity:  0.664

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[2-[2-(dimethylamino)ethyl-methyl-amino]-5-(1H-indazol-3-ylamino)-4-methoxy-phenyl]prop-2-enamide

Formula:  C22H28N6O2

Similarity:  0.6101694915254238

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[2-[2-(dimethylamino)ethyl-methyl-amino]-5-[[6-(4-isoquinolyl)-1H-indazol-3-yl]amino]-4-methoxy-phenyl]prop-2-enamide

Formula:  C31H33N7O2

Similarity:  0.5714285714285714

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[2-[2-(dimethylamino)ethyl-methyl-amino]-4-methoxy-5-[[6-(3-pyridyl)-1H-indazol-3-yl]amino]phenyl]prop-2-enamide

Formula:  C27H31N7O2

Similarity:  0.5522388059701493

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[2-[2-(dimethylamino)ethyl-methyl-amino]-4-methoxy-5-[[6-(1-naphthyl)-1H-indazol-3-yl]amino]phenyl]prop-2-enamide

Formula:  C32H34N6O2

Similarity:  0.5492957746478874

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[2-[2-(dimethylamino)ethyl-methyl-amino]-4-methoxy-5-[[5-(1-naphthyl)-1H-indazol-3-yl]amino]phenyl]prop-2-enamide

Formula:  C32H34N6O2

Similarity:  0.5492957746478874

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[3-[2-[4-[2-(Dimethylamino)ethyl-methylamino]-2-methoxyanilino]-5-methyl-7-oxopyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide

Formula:  C29H33N7O3

Similarity:  0.5467625899280576

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[2-[2-(dimethylamino)ethyl-methyl-amino]-5-[[6-[3-(dimethylamino)phenyl]-1H-indazol-3-yl]amino]-4-methoxy-phenyl]prop-2-enamide

Formula:  C30H37N7O2

Similarity:  0.5357142857142857

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[2-[2-(dimethylamino)ethyl-methyl-amino]-5-[[6-(3-fluorophenyl)-1H-indazol-3-yl]amino]-4-methoxy-phenyl]prop-2-enamide

Formula:  C28H31FN6O2

Similarity:  0.5328467153284672

Relative Targets:   Epidermal growth factor receptor  |

Name:  N-[2-[2-(dimethylamino)ethyl-methyl-amino]-4-methoxy-5-[[6-(4-pyridyl)-1H-indazol-3-yl]amino]phenyl]prop-2-enamide

Formula:  C27H31N7O2

Similarity:  0.5294117647058824

Relative Targets:   Epidermal growth factor receptor  |