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Approved Drugs
Inhibitors
Name:  N-[2-[2-(dimethylamino)ethyl-methyl-amino]-4-methoxy-5-[[5-methyl-4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]phenyl]prop-2-enamide
Formula:  C29H35N7O2
Similarity:  0.8928571428571429
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[5-[[5-cyano-4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]-2-[2-(dimethylamino)ethyl-methyl-amino]-4-methoxy-phenyl]prop-2-enamide
Formula:  C29H32N8O2
Similarity:  0.8695652173913043
Relative Targets:   Epidermal growth factor receptor  |
Name:  Osimertinib
Formula:  C28H33N7O2
Similarity:  0.8103448275862069
Relative Targets:   Epidermal growth factor receptor  | Dipeptidyl peptidase 1  |
Name:  N-[5-[[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]-2-[2-(dimethylamino)ethyl-methyl-amino]-4-methoxy-phenyl]prop-2-enamide
Formula:  C27H30ClN7O2
Similarity:  0.8103448275862069
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[5-[(5-chloro-4-pyrazolo[1,5-a]pyridin-3-yl-pyrimidin-2-yl)amino]-2-[2-(dimethylamino)ethyl-methyl-amino]-4-methoxy-phenyl]prop-2-enamide
Formula:  C26H29ClN8O2
Similarity:  0.7796610169491526
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[2-[2-(Dimethylamino)ethyl-methylamino]-4-methoxy-5-[[6-(1-methylindol-3-yl)pyrazin-2-yl]amino]phenyl]prop-2-enamide
Formula:  C28H33N7O2
Similarity:  0.7647058823529411
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[2-[2-(dimethylamino)ethyl-methyl-amino]-4-methoxy-5-[[2-(1-methylindol-3-yl)pyrimidin-4-yl]amino]phenyl]prop-2-enamide
Formula:  C28H33N7O2
Similarity:  0.7647058823529411
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[4-methoxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]-2-[methyl-[2-(methylamino)ethyl]amino]phenyl]prop-2-enamide
Formula:  C27H31N7O2
Similarity:  0.6910569105691057
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[2-[2-(dimethylamino)ethyl-methyl-amino]-4-methoxy-5-[[6-(1-methylindol-3-yl)-1H-indazol-3-yl]amino]phenyl]prop-2-enamide
Formula:  C31H35N7O2
Similarity:  0.6846153846153846
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[2-[2-(dimethylamino)ethyl-methyl-amino]-5-[[4-(1H-indol-3-yl)pyrimidin-2-yl]amino]-4-methoxy-phenyl]prop-2-enamide
Formula:  C27H31N7O2
Similarity:  0.664
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[2-[2-(dimethylamino)ethyl-methyl-amino]-5-(1H-indazol-3-ylamino)-4-methoxy-phenyl]prop-2-enamide
Formula:  C22H28N6O2
Similarity:  0.6101694915254238
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[2-[2-(dimethylamino)ethyl-methyl-amino]-5-[[6-(4-isoquinolyl)-1H-indazol-3-yl]amino]-4-methoxy-phenyl]prop-2-enamide
Formula:  C31H33N7O2
Similarity:  0.5714285714285714
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[5-[(5-chloro-4-pyrazolo[1,5-a]pyridin-3-yl-pyrimidin-2-yl)amino]-2-[3-(dimethylamino)azetidin-1-yl]-4-methoxy-phenyl]prop-2-enamide
Formula:  C26H27ClN8O2
Similarity:  0.5555555555555556
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[2-[2-(dimethylamino)ethyl-methyl-amino]-4-methoxy-5-[[6-(3-pyridyl)-1H-indazol-3-yl]amino]phenyl]prop-2-enamide
Formula:  C27H31N7O2
Similarity:  0.5522388059701493
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[2-[2-(dimethylamino)ethyl-methyl-amino]-4-methoxy-5-[[6-(1-naphthyl)-1H-indazol-3-yl]amino]phenyl]prop-2-enamide
Formula:  C32H34N6O2
Similarity:  0.5492957746478874
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[2-[2-(dimethylamino)ethyl-methyl-amino]-4-methoxy-5-[[5-(1-naphthyl)-1H-indazol-3-yl]amino]phenyl]prop-2-enamide
Formula:  C32H34N6O2
Similarity:  0.5492957746478874
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[5-[[5-Chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]-4-methoxy-2-(4-methylpiperazin-1-yl)phenyl]prop-2-enamide
Formula:  C27H28ClN7O2
Similarity:  0.5474452554744526
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[5-[(5-chloro-4-pyrazolo[1,5-a]pyridin-3-yl-pyrimidin-2-yl)amino]-2-[(3R)-3-(dimethylamino)pyrrolidin-1-yl]-4-methoxy-phenyl]prop-2-enamide
Formula:  C27H29ClN8O2
Similarity:  0.539568345323741
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[2-[2-(dimethylamino)ethyl-methyl-amino]-5-[[6-(3-fluorophenyl)-1H-indazol-3-yl]amino]-4-methoxy-phenyl]prop-2-enamide
Formula:  C28H31FN6O2
Similarity:  0.5328467153284672
Relative Targets:   Epidermal growth factor receptor  |