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Approved Drugs
Inhibitors
Name:  Egfr-IN-1
Formula:  C28H30N6O4
Similarity:  0.8151260504201681
Relative Targets:   Epidermal growth factor receptor  | Receptor tyrosine-protein kinase erbB-4  |
Name:  N-[3-[2-[4-[2-(dimethylamino)ethyl-methyl-amino]-2-methoxy-anilino]-5-isopropyl-6,7-dioxo-pteridin-8-yl]phenyl]prop-2-enamide
Formula:  C30H36N8O4
Similarity:  0.7441860465116279
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[[2-[4-[2-(dimethylamino)ethyl-methyl-amino]-2-methoxy-anilino]-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide
Formula:  C29H33N7O3
Similarity:  0.7109375
Relative Targets:   Tyrosine-protein kinase JAK3  |
Name:  N-[3-[2-[2-methoxy-4-(3,4,5-trimethylpiperazin-1-yl)anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide
Formula:  C31H35N7O3
Similarity:  0.6716417910447762
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[2-[4-(3,4-dimethylpiperazin-1-yl)-2-methoxy-anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide
Formula:  C30H33N7O3
Similarity:  0.6691729323308271
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[2-[2-Methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxopyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide
Formula:  C29H31N7O3
Similarity:  0.6666666666666666
Relative Targets:   Epidermal growth factor receptor  | Tyrosine-protein kinase JAK3  |
Name:  N-[3-[2-[[1-[2-(dimethylamino)ethyl]pyrazol-4-yl]amino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide
Formula:  C24H26N8O2
Similarity:  0.64
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[[2-[4-[2-(dimethylamino)ethyl-methyl-amino]-2-methoxy-anilino]pyrimidin-4-yl]carbamoylamino]phenyl]prop-2-enamide
Formula:  C26H32N8O3
Similarity:  0.6259541984732825
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[2-[4-[2-(dimethylamino)ethoxy]-2-methoxy-anilino]-5-isopropyl-6,7-dioxo-pteridin-8-yl]phenyl]prop-2-enamide
Formula:  C29H33N7O5
Similarity:  0.6159420289855072
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[7-[4-(dimethylamino)-2-methoxy-anilino]-3-methyl-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]phenyl]prop-2-enamide
Formula:  C25H27N7O3
Similarity:  0.5923076923076923
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]methyl]phenyl]prop-2-enamide
Formula:  C30H33N7O3
Similarity:  0.5815602836879432
Relative Targets:   Tyrosine-protein kinase JAK3  |
Name:  N-[3-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]-5-methyl-phenyl]prop-2-enamide
Formula:  C30H33N7O3
Similarity:  0.5633802816901409
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[5-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]-2-methyl-phenyl]prop-2-enamide
Formula:  C30H33N7O3
Similarity:  0.5633802816901409
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-ethyl-5-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide
Formula:  C31H35N7O3
Similarity:  0.5625
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-isopropyl-5-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide
Formula:  C32H37N7O3
Similarity:  0.5547945205479452
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-fluoro-5-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide
Formula:  C29H30FN7O3
Similarity:  0.5524475524475524
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-bromo-5-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide
Formula:  C29H30BrN7O3
Similarity:  0.5524475524475524
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-chloro-5-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide
Formula:  C29H30ClN7O3
Similarity:  0.5524475524475524
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-tert-butyl-5-[2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]-5-methyl-7-oxo-pyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide
Formula:  C33H39N7O3
Similarity:  0.5472972972972973
Relative Targets:   Epidermal growth factor receptor  |