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Approved Drugs
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Inhibitors
Name:  (E)-N-[3-[[5-Chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]-4-methoxyphenyl]-4-(dimethylamino)but-2-enamide
Formula:  C25H25ClN6O2
Similarity:  0.7941176470588235
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[[5-Chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]phenyl]prop-2-enamide
Formula:  C21H16ClN5O
Similarity:  0.7578947368421053
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[4-[[5-Chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]phenyl]prop-2-enamide
Formula:  C21H16ClN5O
Similarity:  0.7395833333333334
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[(5-Chloro-4-pyrazolo[1,5-a]pyridin-3-ylpyrimidin-2-yl)amino]-4-methoxyphenyl]prop-2-enamide
Formula:  C21H17ClN6O2
Similarity:  0.7029702970297029
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[5-[[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]-2-[2-(dimethylamino)ethyl-methyl-amino]-4-methoxy-phenyl]prop-2-enamide
Formula:  C27H30ClN7O2
Similarity:  0.6666666666666666
Relative Targets:   Epidermal growth factor receptor  |
Name:  1-[6-[[5-Chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]-5-methoxy-2,3-dihydroindol-1-yl]prop-2-en-1-one
Formula:  C24H20ClN5O2
Similarity:  0.6635514018691588
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[5-[[5-Chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]-4-methoxy-2-(4-methylpiperazin-1-yl)phenyl]prop-2-enamide
Formula:  C27H28ClN7O2
Similarity:  0.6551724137931034
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[6-[(3R)-3-[[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]piperidine-1-carbonyl]-3-pyridyl]prop-2-enamide
Formula:  C26H24ClN7O2
Similarity:  0.5702479338842975
Relative Targets:   Cyclin-dependent kinase 12  |
Name:  (E)-N-[3-[(5-Chloro-4-pyrazolo[1,5-a]pyridin-3-ylpyrimidin-2-yl)amino]-4-methoxyphenyl]-4-(dimethylamino)but-2-enamide
Formula:  C24H24ClN7O2
Similarity:  0.5641025641025641
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-[(3R)-3-[[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]-1-piperidyl]-3-fluoro-phenyl]but-2-enamide
Formula:  C27H26ClFN6O
Similarity:  0.5573770491803278
Relative Targets:   Cyclin-dependent kinase 12  |
Name:  N-[2-[2-(dimethylamino)ethyl-methyl-amino]-5-[[4-(1H-indol-3-yl)pyrimidin-2-yl]amino]-4-methoxy-phenyl]prop-2-enamide
Formula:  C27H31N7O2
Similarity:  0.5537190082644629
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-[(1R,3R)-3-[[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]cyclohexoxy]-3-fluoro-phenyl]-4-(dimethylamino)but-2-enamide
Formula:  C30H32ClFN6O2
Similarity:  0.5461538461538461
Relative Targets:   Cyclin-dependent kinase 12  |
Name:  N-[5-[[4-(1H-Indol-3-yl)pyrimidin-2-yl]amino]-4-methoxy-2-(4-methylpiperazin-1-yl)phenyl]prop-2-enamide
Formula:  C27H29N7O2
Similarity:  0.5447154471544715
Relative Targets:   Epidermal growth factor receptor  |
Name:  N-[3-[5-chloro-2-(4-fluoro-2-methoxy-anilino)pyrimidin-4-yl]oxyphenyl]prop-2-enamide
Formula:  C20H16ClFN4O3
Similarity:  0.5412844036697247
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-[(3R)-3-[[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]-1-piperidyl]phenyl]but-2-enamide
Formula:  C27H27ClN6O
Similarity:  0.5284552845528455
Relative Targets:   Cyclin-dependent kinase 12  |
Name:  (E)-N-[6-[(3R)-3-[[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]-1-piperidyl]-3-pyridyl]but-2-enamide
Formula:  C26H26ClN7O
Similarity:  0.5284552845528455
Relative Targets:   Cyclin-dependent kinase 12  |
Name:  (E)-N-[4-[(1R,3R)-3-[[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]cyclohexoxy]phenyl]but-2-enamide
Formula:  C28H28ClN5O2
Similarity:  0.528
Relative Targets:   Cyclin-dependent kinase 12  |
Name:  N-[5-[[5-chloro-4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]-2-[2-(dimethylamino)ethyl-methyl-amino]-4-methoxy-phenyl]prop-2-enamide
Formula:  C28H32ClN7O2
Similarity:  0.5238095238095238
Relative Targets:   Epidermal growth factor receptor  |
Name:  (E)-N-[4-[(3R)-3-[[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]-1-piperidyl]-5-methoxy-2-methyl-phenyl]but-2-enamide
Formula:  C29H31ClN6O2
Similarity:  0.5234375
Relative Targets:   Cyclin-dependent kinase 12  |