UDP-N-acetylmuramoylalanine--D-glutamate ligase
Target information
- CovInDB Protein
- P14900
- Name
- UDP-N-acetylmuramoylalanine--D-glutamate ligase
- Encoding Gene
- murD
- Synonyms
-
- D-glutamic acid-adding enzyme
- UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
- Taxonomy
- Escherichia coli (strain K12)
- Description
-
Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
- Sequence
-
MADYQGKNVVIIGLGLTGLSCVDFFLARGVTPRVMDTRMTPPGLDKLPEAVERHTGSLNDEWLMAADLIVASPGIALAHPSLSAAADAGIEIVGDIELFCREAQAPIVAITGSNGKSTVTTLVGEMAKAAGVNVGVGGNIGLPALMLLDDECELYVLELSSFQLETTSSLQAVAATILNVTEDHMDRYPFGLQQYRAAKLRIYENAKVCVVNADDALTMPIRGADERCVSFGVNMGDYHLNHQQGETWLRVKGEKVLNVKEMKLSGQHNYTNALAALALADAAGLPRASSLKALTTFTGLPHRFEVVLEHNGVRWINDSKATNVGSTEAALNGLHVDGTLHLLLGGDGKSADFSPLARYLNGDNVRLYCFGRDGAQLAALRPEVAEQTETMEQAMRLLAPRVQPGDMVLLSPACASLDQFKNFEQRGNEFARLAKELG
- Active Site
-
Feature Key Position(s) Description None None None - Structure
-
PDB: 2X5O
Show SurfaceSite View - Reference
- UniProt
Covalent Inhibitors
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