Transthyretin
Target information
- CovInDB Protein
- P02766
- Name
- Transthyretin
- Encoding Gene
- TTR
- Synonyms
-
- Transthyretin
- ATTR
- Prealbumin
- TBPA
- Taxonomy
- Homo sapiens (Human)
- Description
-
Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.
- Sequence
-
MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE
- Active Site
-
Feature Key Position(s) Description Binding site 35 Thyroid hormones Binding site 74 Thyroid hormones - Structure
-
Check covalent ligand-protein complexes.
PDB: 4FI7
Show SurfaceSite View - Reference
- UniProt
Covalent Inhibitors
| Structure | Rank | ID | Warhead | Reaction Mechanism | Target Site | Activity Type | Relation | Value | Unit | Experiment Method | Assay | Reference |
|---|