6BV8
Target information
- RCSB PDB
- 6BV8
- Title
- Structure of proteinaceous RNase P 1 (PRORP1) from A. thaliana complexed with Mn after 3-hour soak with juglone
- Method
- X-RAY DIFFRACTION
- Resolution
- 2.1
- Classification
- HYDROLASE/HYDROLASE INHIBITOR
- Organism
- Arabidopsis thaliana
- Protein
- Proteinaceous RNase P 1, chloroplastic/mitochondrial (Q66GI4)
- Year
- 2017
- Publication Title
- Inhibition of protein-only RNase P with Gambogic acid and Juglone
- Abstract
-
Not Available
- External Link
- RCSB PDB
Ligand information
- HET
- JUG
- Chain ID
- A
- HET Number
- 601
- Molecular Formula
- C10H6O3
- Structure
-
- IUPAC Name
- 5-hydroxynaphthalene-1,4-dione
- InChI
- InChI=1S/C10H6O3/c11-7-4-5-9(13)10-6(7)2-1-3-8(10)12/h1-5,12H
- InChI Key
- KQPYUDDGWXQXHS-UHFFFAOYSA-N
- Canonical SMILES
- Oc1cccc(c12)C(=O)C=CC2=O
- Bioactivity data
- CI000005
Covalent Binding
- Warhead
- Michael Acceptor
- Reaction Mechanism
- Michael Addition
- Residue
- CYS : 353
- Residue Chain
- A
- Interactions
- Pharmacophore Model